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Hydrangea macrophylla is a flowering plant that changes color of the bloom in response to soil pH. Ferdoush et al. demonstrate a metaphorical mimicry of such a phenomenon at the level of gene activation, where the activator in budding yeast functionally alternates between coactivators, SAGA and NuA4, in response to inorganic phosphate in the growth medium to promote transcription of a high-affinity inorganic phosphate transporter gene, PHO84. Image courtesy of Arpan Roy. See Ferdoush et al. GENETICS 208: 191–205.

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Community Voices

TAGC Keynote Speaker Snapshot: Caroline Dean

Get to know the TAGC 2020 Keynote Speakers through our interview series. Caroline Dean has been a project leader at the John Innes Centre Norwich since 1988. Her work on seasonal timing mechanisms in plants has led into a detailed mechanistic analysis of the regulation of the floral repressor FLC in Arabidopsis. FLC transcription is […]

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by Sarah Bay

Invasion and Extinction Dynamics of Mating Types Under Facultative Sexual Reproduction [Population and Evolutionary Genetics]

In sexually reproducing isogamous species, syngamy between gametes is generally not indiscriminate, but rather restricted to occurring between complementary self-incompatible mating types. A longstanding question regards the evolutionary pressures that control the number of mating types observed in natural populations, which ranges from two to many thousands. Here, we describe a population genetic null model of this reproductive system, and derive expressions for the stationary probability distribution of the number of mating types, the establishment...

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by Czuppon, P., Constable, G. W....

Involvement of a G Protein Regulatory Circuit in Alternative Oxidase Production in Neurospora crassa

The Neurospora crassa nuclear aod-1 gene encodes an alternative oxidase that functions in mitochondria. The enzyme provides a branch from the standard electron transport chain by transferring electrons directly from ubiquinol to oxygen. In standard laboratory strains, aod-1 is transcribed at very low levels under normal growth conditions. However, if the standard electron transport chain is disrupted, aod-1 mRNA expression is induced and the AOD1 protein is produced. We previously identified a strain of N....

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by Bosnjak, N., Smith, K. M.,...

Close-up view of a wild-type Junonia coenia wing eyespot pattern. Zhang et al. used CRISPR mutagenesis to interfere with the genetic machinery necessary for making melanin pigments in the colored scales of the butterfly wing. See Zhang et al.

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Jennifer Solis, Northwestern University

It was critical that GSA was so willing to put their faith in us. Many people didn’t initially have a lot of confidence that a group of postdocs could organize a new event of this scale.

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