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Hydrangea macrophylla is a flowering plant that changes color of the bloom in response to soil pH. Ferdoush et al. demonstrate a metaphorical mimicry of such a phenomenon at the level of gene activation, where the activator in budding yeast functionally alternates between coactivators, SAGA and NuA4, in response to inorganic phosphate in the growth medium to promote transcription of a high-affinity inorganic phosphate transporter gene, PHO84. Image courtesy of Arpan Roy. See Ferdoush et al. GENETICS 208: 191–205.

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Careers

What you’ll get from TAGC’s Industry Sessions

Students, postdocs, academic faculty, and industry researchers will all find benefits at the new Industry Sessions at TAGC, to be held April 22–26 2020 in the Washington DC region. When industry scientists and academic labs collaborate, both society and science benefit. That’s one of two big-picture messages Kailene Simon hopes will be conveyed through a […]

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by Cristy Gelling

Distinct Elements Confer the Blocking and Bypass Functions of the Bithorax Fab-8 Boundary [Gene Expression]

Boundaries in the Drosophila bithorax complex (BX-C) enable the regulatory domains that drive parasegment-specific expression of the three Hox genes to function autonomously. The four regulatory domains (iab-5, iab-6, iab-7, and iab-8) that control the expression of the Abdominal-B (Abd-B) gene are located downstream of the transcription unit, and are delimited by the Mcp, Fab-6, Fab-7, and Fab-8 boundaries. These boundaries function to block cross talk between neighboring regulatory domains. In addition, three of the...

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by Kyrchanova, O., Wolle, D., Sabirov,...

Single-Step Genome-Wide Association Study for Resistance to Piscirickettsia salmonis in Rainbow Trout (Oncorhynchus mykiss)

One of the main pathogens affecting rainbow trout (Oncorhynchus mykiss) farming is the facultative intracellular bacteria Piscirickettsia salmonis. Current treatments, such as antibiotics and vaccines, have not had the expected effectiveness in field conditions. Genetic improvement by means of selection for resistance is proposed as a viable alternative for control. Genomic information can be used to identify the genomic regions associated with resistance and enhance the genetic evaluation methods to speed up the genetic improvement...

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by Barria, A., Marin-Nahuelpi, R., Caceres,...

Close-up view of a wild-type Junonia coenia wing eyespot pattern. Zhang et al. used CRISPR mutagenesis to interfere with the genetic machinery necessary for making melanin pigments in the colored scales of the butterfly wing. See Zhang et al.

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Jennifer Solis, Northwestern University

It was critical that GSA was so willing to put their faith in us. Many people didn’t initially have a lot of confidence that a group of postdocs could organize a new event of this scale.

Sarah Dykstra, Career Development Symposium funding recipient
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