Subscribe to GENETICS

GSA members receive a free individual subscription to GENETICS.

Already a GSA member?

Activate your subscription using the ID number listed in your GSA membership email confirmation (sent from society@genetics-gsa.org). Once you have your ID number, follow the link below to activate your subscription.
Activate GENETICS subscription

For assistance, email us at genetics-gsa@thegsajournals.org

Not a member?

A subscription to GENETICS is just one of many benefits of membership. If you’re not sure whether you’re a member, you can check your membership status.
Join GSA

Read the latest from GENETICS Early Online

Growth-Dependent Activation of Protein Kinases Suggests a Mechanism for Measuring Cell Growth [Investigation]

In all cells, progression through the cell cycle occurs only when sufficient growth has occurred. Thus, cells must translate growth into a proportional signal that can be used to measure and transmit information about growth. Previous genetic studies in budding yeast suggested that related kinases called Gin4 and Hsl1 could function in mechanisms that measure bud growth; however, interpretation of the data was complicated by the use of gene deletions that cause complex terminal phenotypes....

Read more »

by Jasani, A., Huynh, T., Kellogg,...

Base-Pairing Requirements for Small RNA-Mediated Gene Silencing of Recessive Self-Incompatibility Alleles in Arabidopsis halleri [Investigation]

Small non-coding RNAs are central regulators of genome activity and stability. Their regulatory function typically involves sequence similarity with their target sites, but understanding the criteria by which they specifically recognize and regulate their targets across the genome remains a major challenge in the field, especially in the face of the diversity of silencing pathways involved. The dominance hierarchy among self-incompatibility alleles in Brassicaceae is controlled by interactions between a highly diversified set of small...

Read more »

by Burghgraeve, N., Simon, S., Barral,...

Evolutionary Rescue and Drug Resistance on Multicopy Plasmids [Investigation]

Bacteria often carry "extra DNA" in form of plasmids in addition to their chromosome. Many plasmids have a copy number greater than one such that the genes encoded on these plasmids are present in multiple copies per cell. This has evolutionary consequences by increasing the mutational target size, by prompting the (transitory) co-occurrence of mutant and wild-type alleles within the same cell, and by allowing for gene dosage effects. We develop and analyze a mathematical...

Read more »

by Santer, M., Uecker, H.